李先纬, 男，副教授，博士生导师，广东工业大学青年百人A类人才引进。主要研究方向为：金属有机化学，绿色化学导向的有机合成及其在有机光电材料中的应用，在Angew. Chem. Int. Ed.，Chem. Sci.，ACS Catal., Sci. Chin. Chem.，等高水平国际期刊上发表论文50余篇，授权专利30余项，参与华南理工大学江焕峰教授主持的教育部自然科学进步一等奖。

联系方式：Email: xwli@gdut.edu.cn; Tel: 15989188462

教育背景：

2016.7–至今 广东工业大学轻工化工学院，“青年百人A”，副教授，博士生导师；

2019.3–2020.3 麦吉尔大学（McGill University）访问学者，合作导师：李朝军（Chao-Jun Li）教授（加拿大科学院院士）；

2014. 7–2016-7 南开大学元素有机国家重点实验室，北京大学化学与分子工程学院，博士后，合作导师：梁广鑫教授，施章杰教授（国家杰青，教育部长江学者）；

2009. 9–2014. 6 华南理工大学，博士（硕博连读），导师：江焕峰 教授（国家杰青）；

2005.09–2009.06 安徽工业大学，本科

主持的科研项目：

国家级科研项目：

1、 国家自然科学基金面上项目：基于金属催化有序碳氢键和碳碳键活化策略构建稠杂环；项目批准号：22071034，2021-2024，主持；

2、 国家自然科学基金青年项目：基于钌–铜双金属催化惰性C–H键和醇类C–O键的炔基化反应研究；项目批准号：21602032，2017-2019，主持；

部分科研论文：

1．Hulin Zhong, Shixing Cai, Sheng Hu, Yuan Liu, Yang Gao, Qian Chen, Yanping Huo, Xianwei Li*, Haloalkyne-Switched Regiodivergent C−H Annulation of Amides That Tolerates Strongly Coordinating Heterocycles, ACS Catal., 2025, 15, 19994−20003. (IF: 13.700)

2. Ci Chen,^‡ Qiaoya Zhang,^‡ Zhiwei Huang, Wensen Ouyang, Yang Gao, Jiye Luo, Yuan Liu, Yanping Huo, Qian Chen, Xianwei Li*, Ru(II)-catalyzed regioselective oxidative Heck reaction with internal olefins that tolerated strongly coordinating heterocycles, Chem. Sci., 2024, 15, 20064–20072.

3. Xianwei Li,* Jianhang Rao, Wensen Ouyang, Qian Chen, Ning Cai, Yu-Jing Lu, Yanping Huo. Sequential C−H and C−C Bond Cleavage: Divergent Constructions of Fused NHeterocycles via Tunable Cascade, ACS Catal., 2019, 9, 8749−8756.

4. Qiaoya Zhang, Yinling Li, Yabo Chen, Jiahua Jiang, Yuan Liu, Jiye Luo, Yang Gao, Yanping Huo, Qian Chen, Xianwei Li*, Ru(II)-Catalyzed Divergent C−H Alkynylation Cascade with Bifunctional α‑Alcohol Haloalkynes, Org. Lett., 2024, 26, 2186−2191.

5. Zhongyuan Li, Xiaojian Chen, Hulin Zhong, Yitong Lin, Yang Gao, Yuan Liu, Qian Chen, Yanping Huo, Xianwei Li*, Expedient Delivery of Quinolinone Drugs via a Traceless N-nitroso Enabled Oxidative Heck/amidation Cascade, Chem. Commun., 2022, 58, 13959–13962.

6. Wensen Ouyang, Xiaoqing Cai, Xiaojian Chen, Jie Wang, Jianhang Rao, Yang Gao, Yanping Huo, Qian Chen, Xianwei Li*, Sequential C–H Activation Enabled Expedient Delivery of Polyfunctional Arenes, Chem. Commun., 2021, 57, 8075–8078.

7. Bairong Liu, Jianhang Rao, Weibing Liu, Yang Gao, Yanping Huo, Qian Chen, Xianwei Li*, Ligand Assisted, Olefins Switched Divergent Oxidative Heck Cascade with Molecular Oxygen Enabled by Self-Assembled Imines. Org. Chem. Front., 2023, 10, 2128–2137. (Front Cover, 年度最佳OCF论文)

8. Wensen Ouyang, Bairong Liu, Yi He, Yanmei Wen, Yang Gao, Yanping Huo, Qian Chen, Xianwei Li*, Modular Construction of Functionalized Anilines via Switchable C–H and N-Alkylations of Traceless N-Nitroso Anilines with Olefins, Org. Chem. Front., 2022, 9, 2746–2752. (Invited contribution, Highlight by Frontiers Journal)

9. Aidong Huang, Yishen Han, Peiqing Wu, Yang Gao, Yanping Huo, Qian Chen, Xianwei Li*, Ligand Accelerated Site-Selective Csp²–H and Csp³–H Alkynylation of Alcohols via Pd(II) Catalysis, Org. Chem. Front., 2021, 8, 6484–6490. (Front Cover)

10. Xianwei Li, Guangxin Liang,* Zhang-Jie Shi,* Regio-Divergent C‒H Alkynylation with Janus Directing Strategy via Ir(III) Catalysis, Chin. J. Chem., 2020, 38, 929-934. (Front Cover, selected as ‘Break Report’, Highlighted by Chin. J. Chem.)

11. Guocai Wu, Wensen Ouyang, Qian Chen, Yanping Huo, Xianwei Li,* Cross-Dehydrogenative Alkynylation of Sulfonamides and Amides with Terminal Alkynes via Ir(III) Catalysis, Org. Chem. Front., 2019, 6, 284-289. (Front Cover, Hot Paper)

12. Bifu Liu,^† Qiaoya Zhang,^†Aidong Huang,^† Hulin Zhong, Xiaojian Chen, Kejun Feng, Yang Gao, Yanping Huo, Qian Chen, Xianwei Li*, Amide-Enabled Distal and Multiple Dehydrogenative C−H Alkynylation with Tuning Site Selectivity, Org. Lett., 2025, 27, 8446−8451.

13. Xianwei Li, Chao-Jun Li*, A Cu/Cinchona P, N-ligand System Enabled General Asymmetric C(sp³)–C(sp) Coupling, Sci. China Chem., 2020, 63, 751-752. (IF: 10.138)

14. Xianwei Li, Xiaohang Liu, Huoji Chen, Wanqing Wu, Chaorong Qi, Huanfeng Jiang*. Copper-Catalyzed Aerobic Oxidative Transformation of Ketone-Derived N-Tosyl Hydrazones: An Entry to Alkynes. Angew. Chem. Int. Ed., 2014, 53, 14485–144895.

15. Xianwei Li, Liangbin Huang, Huoji Chen, Wanqing Wu, Huawen Huang, Huanfeng Jiang*. Copper-Catalyzed Oxidative [2+2+1] Cycloaddition: Regioselective Synthesis of 1,3-Oxazoles from Internal Alkynes and Nitriles. Chem. Sci., 2012, 3, 3463–3467.