讲座嘉宾：孙建伟 教授（香港科技大学）

讲座主持：霍延平 教授

讲座时间：2019年05月29日（周三）上午10:00-12:00

讲座地点：实验四号楼213

主讲人简介：

Jianwei Sun received his B.S. from Nanjing University (2001), M.S. in Organic Chemistry from Nanjing University (2004) and Ph.D. from the University of Chicago (2008). He conducted the postdoctoral research at Massachusetts Institute of Technology. He joined the Hong Kong University of Science and Technology in 2010 and became an associate professor since 2015.His research program is focused on the development of new methods for organic synthesis, with an emphasis on organocatalysis and he is also interested in applying our new methods in the synthesis of useful molecules, such as biologically active compounds and light-harvesting materials. So far he has published >76 peer reviewed articles. He has won many honors such as NHU-CJC Innovation Award,Chinese Journal of Chemistry(2018),Asian Core Program Lectureship Award (2017, by Japan), Asian Core Program Lectureship Award (2015, by Korea).

报告摘要：Alkynes are readily available chemical feedstock. Selective functionalization of alkynes provides rapid access to functionalized olefins. While regio- and stereoselectivity for the functionalization of terminal alkynes can be well-controllable by tuning the conditions and metal catalyst, it remains challenging for internal alkynes. Furthermore, electron-rich alkynes remaining underexplored. In this talk, I will present our recent progress in utilizing electron-rich alkynes for a range of highly selective functionalizations, such as hydrosilylation and hydroboration. Moreover, medium ring lactones and lactams are widespread subunits in biologically active compounds and natural products. The development of efficient strategies for their assembly has been a longstanding topic in organic synthesis. Although significant progress has been achieved in the past few decades, new strategies are in high demand. I will also introduce our effort in utilizing a special type of electron-rich alkynes, siloxy alkynes, for the development of several intermolecular reactions leading to the efficient synthesis of medium ring systems.